BPC-157/TB-500 Blend (10 Vial Box)

Compliance & Disclaimer

• For Research Use Only
• Not FDA or EMA approved for clinical application
• Evidence is limited to preclinical studies; safety and efficacy in humans remain unestablished.

This peptide combination is studied in preclinical research settings for its potential to influence tissue repair and regeneration. Both compounds are classified as investigational agents and are not approved for human or veterinary use. Current evidence is derived from animal models and in vitro assays; no therapeutic claims are made.

Mechanistic Insights

• BPC-157: A stable pentadecapeptide originally isolated from a gastric protein. Research suggests it may:

  • Promote angiogenesis via VEGF and nitric oxide pathways
  • Support fibroblast migration and collagen organization in tendon and ligament models
  • Modulate inflammatory signaling, reducing cytokines such as IL-6 and TNF-α

• TB-500: A synthetic fragment of Thymosin Beta-4, involved in cytoskeletal regulation. Studies indicate it may:

  • Enhance cell motility through actin polymerization
  • Stimulate angiogenesis and extracellular matrix remodeling
  • Contribute to inflammation control and tissue resilience

Research Applications

• Musculoskeletal Injury Models: Preclinical data show accelerated healing in tendons, ligaments, and muscle tissue.
• Microcirculation Restoration: BPC-157 has demonstrated effects on vascular integrity, while TB-500 aids cellular migration to injury sites.
• Synergistic Potential: Combining these peptides may amplify angiogenesis and structural repair processes, as observed in rodent studies.

Key Peer-Reviewed References

• Sikiric P. et al. BPC-157 and Vascular Healing: Preclinical Evidence. Curr Pharm Des. 2020;26(3): DOI:10.2174/1381612826666200127110543
• Chang J. et al. Thymosin Beta-4 and Tissue Regeneration: Mechanistic Insights. Ann N Y Acad Sci. 2019;1445(1): DOI:10.1111/nyas.14058
• Sikiric P., Seiwerth S. BPC-157 in Tendon and Ligament Repair: Animal Model Studies. J Orthop Res. 2021;39(8): DOI:10.1002/jor.24987
• Goldstein A.L. et al. Thymosin Beta-4 and Derivatives in Wound Healing. Expert Opin Biol Ther. 2018;18(1): DOI:10.1080/14712598.2018.1409723